A SpaceX Falcon 9 rocket launched the 25th Commercial Resupply Services (CRS-25) mission for NASA to the International Space Station at 8:44 p.m. on 14 July 2022 from Launch Complex 39A (LC-39A) at Kennedy Space Center. Following stage separation, Falcon 9 landed on the A Shortfall of Gravitas droneship stationed in the Atlantic Ocean.

This is the fifth flight of the first stage booster supporting this mission, which previously supported CRS-22, Crew-3, Turksat 5B, and Crew-4. The Dragon supporting this mission previously supported CRS-21 and CRS-23. Approximately twelve minutes after liftoff, Dragon will separate from Falcon 9’s second stage and dock to the space station on Saturday, July 16 at 11:20 a.m. ET, 15:20 UTC.

Besides supplies and equipment for the international crew, NASA said, "Dragon will carry more than 5,800 pounds of cargo, including a variety of NASA investigations like NASA’s Earth Surface Mineral Dust Source Investigation (EMIT), which will identify the composition of mineral dust from Earth’s arid regions and analyze dust carried through the atmosphere from deserts to see what effects it has on the planet, further advancing NASA’s data contributions to monitoring climate change.

Other investigations include studying the aging of immune cells and the potential to reverse those effects during postflight recovery, a CubeSat that will monitor cloud top and ocean surface temperatures which could help scientists understand Earth’s climate and weather systems, and a student experiment testing a concrete alternative for potential use in future lunar and Martian habitats."